Potential of vitamin E as an antioxidant adjunct in Wilson's disease.
Med Hypotheses
; 73(6): 1029-30, 2009 Dec.
Article
em En
| MEDLINE
| ID: mdl-19581055
ABSTRACT
Wilson's disease is a rare genetic illness of copper metabolism, which leads to copper-overload in mitochondria and organ damage, especially to the liver. Oxidative stress is central to the pathogenesis and a case is briefly made for rigorous trials of vitamin E as an antioxidant adjunct based on earlier corollary studies of its levels in the blood and liver of Wilson's disease patients and its effects in animal models of the illness.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vitamina E
/
Degeneração Hepatolenticular
/
Antioxidantes
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article