PCI complexes: Beyond the proteasome, CSN, and eIF3 Troika.
Mol Cell
; 35(3): 260-4, 2009 Aug 14.
Article
em En
| MEDLINE
| ID: mdl-19683491
ABSTRACT
The bipartite PCI domain serves as the principal scaffold for proteasome lid, CSN, and eIF3, complexes that influence protein life span. PCI domains are also found in newly identified complexes directing nucleic acid regulation. The breadth of functions associated with the extended PCI family is a factor of shared subunits, among them a common factor Sem1/DSS1 that facilitates complex assembly.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeo Hidrolases
/
Fator de Iniciação 3 em Eucariotos
/
Complexos Multiproteicos
/
Complexo de Endopeptidases do Proteassoma
/
Modelos Biológicos
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article