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The antecedents of non-affective psychosis in a birth-cohort, with a focus on measures related to cognitive ability, attentional dysfunction and speech problems.
Welham, J; Scott, J; Williams, G M; Najman, J M; Bor, W; O'Callaghan, M; McGrath, J.
Afiliação
  • Welham J; Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia.
Acta Psychiatr Scand ; 121(4): 273-9, 2010 Apr.
Article em En | MEDLINE | ID: mdl-19694626
OBJECTIVE: Adults with non-affective psychosis show subtle deviations in a range of developmental trajectories as children and adolescents. METHOD: Based on a birth-cohort (n = 3801), we examined the Peabody Picture Vocabulary Test (PPTV) at age 5, and Raven's Standard Progressive Matrices (RSPM) and Wide Range Achievement Test reading scale (WRAT-R) at age 14. Items related to speech problems and attentional dysfunction were available from maternal- or self-report. At age 21, we identified 60 cohort members who were screen-positive for non-affective psychosis (SP-NAP). RESULTS: Impaired performance on the PPVT and RSPM (but not WRAT-R) predicted SP-NAP for males only. Male cohort members in the highest quartile for attentional dysfunction at ages 5 and 14 were about 5-8 times more likely to develop SP-NAP. SP-NAP in males was significantly associated with speech problems at age 14. CONCLUSION: Males who develop non-affective psychoses have subtle impairments in cognitive capacity prior to the development of their psychotic disorder.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Esquizofrenia Paranoide / Transtorno do Deficit de Atenção com Hiperatividade / Distúrbios da Fala / Transtornos Cognitivos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2010 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Esquizofrenia Paranoide / Transtorno do Deficit de Atenção com Hiperatividade / Distúrbios da Fala / Transtornos Cognitivos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2010 Tipo de documento: Article