Banana peel extract suppressed prostate gland enlargement in testosterone-treated mice.
Biosci Biotechnol Biochem
; 73(9): 1911-4, 2009 Sep.
Article
em En
| MEDLINE
| ID: mdl-19734683
ABSTRACT
A methanol extract of banana peel (BPEx, 200 mg/kg, p.o.) significantly suppressed the regrowth of ventral prostates and seminal vesicles induced by testosterone in castrated mice. Further studies in the androgen-responsive LNCaP human prostate cancer cell line showed that BPEx inhibited dose-dependently testosterone-induced cell growth, while the inhibitory activities of BPEx did not appear against dehydrotestosterone-induced cell growth. These results indicate that methanol extract of banana peel can inhibit 5alpha-reductase and might be useful in the treatment of benign prostate hyperplasia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hiperplasia Prostática
/
Testosterona
/
Extratos Vegetais
/
Musa
Limite:
Animals
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article