[Effect of HA/TiO2 coating titanium surface on the growth of MG63].

PURPOSE: To evaluate the bioactivity of titanium surface treated by micro-arc oxidation (MAO) combined with ion beam assisted deposition (IBAD). METHODS: Titanium surfaces were treated by machined(S0), micro-arc oxidation(S1) and micro-arc oxidation combined with IBAD(S2), respectively. The topography and roughness of surfaces were determined by profilometer, and the bioactivity of the surface was evaluated by CLSM, MTT assay and ALP activity of cells. The data was analyzed by one-way ANOVA using SPSS11.0 software. RESULTS: The surfaces of S2 group were smoother than those of S1 group. On day 5, the OD value of S2 group was the highest among the three groups.10 days later, ALP activity on S1 and S2 groups were higher than that of S0 group. CONCLUSIONS: It is concluded that IBAD technique which provides HA coating on MAO surface could reinforce the bioactivity of micro-arc oxidation and could have a rapid osseointegration.