The impact of PET/CT on therapeutic strategy of patients with colorectal cancer metastasis.
Hepatogastroenterology
; 56(93): 968-70, 2009.
Article
em En
| MEDLINE
| ID: mdl-19760922
ABSTRACT
BACKGROUND/AIMS:
The study's aim was to assess the impact of the PET/CT on the therapeutic strategy of the patients with colorectal cancer metastasis.METHODOLOGY:
Fifteen patients who were suspicious of postoperative colorectal cancer metastasis were included in the study. Each patient received a positron emission tomography/computed tomography (PET/CT) after received contrast-enhanced computed tomography (ceCT). The therapeutic strategies were made before and after the PET/ CT respectively. The lesions confirmed by pathology or periodic follow up of ceCT (3 and 6 mo).RESULTS:
Intrahepatic metastases were present in 5 of the 15 patients, total 9 lesions. The specificities of the PET/CT and ceCT were 100%. The patients with intrahepatic metastases were detected by PET/CT and ceCT with a sensitivity of 100% and 80%, respectively (p = 0.0009). Extrahepatic metastases were present in 11 of the 15 patients, total 32 lesions. The specificities of the PET/CT and ceCT were 75% and 50%, respectively. PET/ CT and ceCT were with a sensitivity of 100% and 63.6%, respectively (p = 0.0177). The therapeutic strategies were changed after received PET/CT in 6 (40%) of the 15 patients.CONCLUSIONS:
PET/CT is superior to ceCT for the detection of the metastatic lesions of the colorectal cancer, and is a valuable tool to help select the correct therapeutic strategies.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Colorretais
/
Tomografia Computadorizada de Emissão
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Tomografia Computadorizada por Raios X
/
Metástase Neoplásica
Limite:
Adult
/
Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article