Autonomic function during closed loop stimulation and fixed rate pacing: heart rate variability analysis from 24-hour Holter recordings.
Pacing Clin Electrophysiol
; 33(3): 337-42, 2010 Mar.
Article
em En
| MEDLINE
| ID: mdl-19889189
ABSTRACT
AIM:
Aim of this retrospective study was to analyze the effect of closed-loop stimulation (CLS) and DDD pacing mode on autonomic balance, and to evaluate heart rate variability (HRV) during CLS stimulation. METHODS AND MATERIALS Autonomic balance was estimated by a 24-hour HRV analysis of paced and spontaneous beats in patients implanted with a dual-chamber pacemaker (Inos(2+) CLS-Biotronik GmbH, Berlin, Germany) and randomly assigned to CLS or DDD pacing mode. Patients underwent two 24-hour electrocardiogram Holter recordings at the end of each 3-month pacing mode period. Each Holter recording was automatically scanned to extract sequences of consecutive beats of the same type [atrial paced (Ap)-sequence and atrial spontaneous (As)-sequence], lasting at least 130 beats.RESULTS:
Eight hundred and ten sequences were extracted from 15 patients, and the following spectral parameters were evaluated during both CLS and DDD mode the total power (variance), the absolute and percentage (relative to the total power) powers of the low frequency (LF, 0.04-0.15 Hz) and high frequency (HF, 0.15-0.4 Hz) components, as well as the LF/HF power ratio.DISCUSSION:
The two main findings of this study were in all the patients, CLS seems to mimic short-term physiological HRV, although the variability (total power) was lower than that relative to the spontaneous beats; the HRV of the spontaneous beats had an higher LF/HF when the pacemaker was programmed as DDD respect to CLS, consistent with a shift toward sympathetic predominance.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sistema Nervoso Autônomo
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Estimulação Cardíaca Artificial
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Eletrocardiografia Ambulatorial
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Frequência Cardíaca
Tipo de estudo:
Observational_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article