Evaluation of CNS activities of ethanol extract of roots and rhizomes of Cyperus rotundus in mice.
Acta Pol Pharm
; 66(5): 535-41, 2009.
Article
em En
| MEDLINE
| ID: mdl-19894649
ABSTRACT
The ethanol extract of Cyperus rotundus (EECR) was tested for possible pharmacological effects on experimental animals. EECR significantly potentiated the sleeping time of mice induced by standard hypnotics, viz. pentobarbitone sodium, diazepam, and meprobamate in a dose dependent manner. EECR showed significant analgesic properties as evidenced by the significant reduction in the number of writhes and stretches induced in mice by 1.2% acetic acid solution. It also potentiated analgesia induced by morphine and pethidine in mice. Pretreatment with EECR caused significant protection against strychnine and leptazol-induced convulsions. The behavioral studies on mice indicate CNS depressant activity of the ethanol extract of C. rotundus.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extratos Vegetais
/
Depressores do Sistema Nervoso Central
/
Cyperus
Limite:
Animals
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article