A stereoselective approach to nucleosides and 4'-thioanalogues from acyclic precursors.
J Am Chem Soc
; 131(47): 17242-5, 2009 Dec 02.
Article
em En
| MEDLINE
| ID: mdl-19902939
ABSTRACT
D- and L-nucleosides and analogues thereof, including the 4'-thionucleoside series, are one of the most important biological and pharmaceutically active classes of compounds. A novel approach to their synthesis from chiral acyclic thioaminal, bearing the nucleobase, is described.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos de Sulfidrila
/
Nucleosídeos
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article