Fabrication of nano scaled protein monolayer consisting of cytochrome c on self-assembled 11-MUA layer for bioelectronic device.
J Nanosci Nanotechnol
; 9(12): 7136-40, 2009 Dec.
Article
em En
| MEDLINE
| ID: mdl-19908744
ABSTRACT
The biomolecular/organic hetero-structure films (cytochrome c/11-mercapto-undecanoic acid) on gold substrates were controlled and fabricated with molecular level for developing valuable molecular electronic devices. Cytochrome c is a metalloprotein having redox property, which can be directly applicable to biomemory device as a active element. For efficient immobilization of the protein on the gold substrate, 11-mercapto-undecanoic acid (11-MUA) was used as a linker material between protein and inorganic substrate. The proposed nano scaled biomolecular/organic hetero-structure layer (cytochrome c/11-MUA) on gold surface was investigated by using surface plasmon resonance technique. The molecular morphology of the fabricated protein layer was confirmed by scanning tunneling microscopy. Electrochemical properties of fabricated biomolecular/organic hetero layer were verified using cyclic voltammetry. Their redox properties was sustained over 1000 cycles of cyclic voltametry. It proved that the fabricated film was a suitable platform for the bioelectronic device application.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos de Sulfidrila
/
Técnicas Biossensoriais
/
Ressonância de Plasmônio de Superfície
/
Cristalização
/
Citocromos c
/
Nanoestruturas
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Eletrônica
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Ácidos Graxos
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article