Finale: the last minutes of Smads.
Cell
; 139(4): 658-60, 2009 Nov 13.
Article
em En
| MEDLINE
| ID: mdl-19914161
ABSTRACT
TGF-beta ligands induce phosphorylation of receptor-activated Smads at both the C-terminal tail and the linker region. Two papers from Massagué and colleagues (Alarcón et al., 2009; Gao et al., 2009) reveal a dual role for this linker phosphorylation, which is required for activation of Smads and for their degradation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ativação Transcricional
/
Proteínas Smad
Limite:
Animals
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article