[Simulation study of anti-hypoxia active fraction of Xiangdan injection by support vector machine].
Zhong Yao Cai
; 32(8): 1285-7, 2009 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-19960955
OBJECTIVE: To investigate the anti-hypoxia active fraction of Xiangdan injection. METHODS: The anti-hypoxia experiment under normal pressure with mice was adopted on the basis of orthogonal design, and a support vector machine model was established for pharmacodynamics prediction of TCM prescriptions. Moreover, the anti-hypoxia active fraction of Xiangdan injection was determined by experimental confirmation. RESULTS: The prediction model established in this study could predict the drug actions of different formulas. CONCLUSION: As indicated in model prediction and experimental confirmation, the pharmacodynamic actions of several formulas are superior to that of the original formula, and ADE has the best effect.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Algoritmos
/
Inteligência Artificial
/
Medicamentos de Ervas Chinesas
/
Hipóxia
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
Zh
Ano de publicação:
2009
Tipo de documento:
Article