[Argyrophilic grain disease: synergistic component of dementia?]. / Maladie des grains argyrophiles: composante synergique de la démence ?
Rev Neurol (Paris)
; 166(4): 428-32, 2010 Apr.
Article
em Fr
| MEDLINE
| ID: mdl-19963233
ABSTRACT
INTRODUCTION:
Argyrophilic grain disease (AGD) is one cause of neurodegenerative dementia with a variable clinical spectrum. A neuropathology study is required for diagnosis. CASE REPORT We report the case of a 68-year-old patient presenting with cognitive decline associating with frontal dysfunction and parkinsonism. Death occurred two years after onset. The neuropathology study revealed a status criblosus in the basal ganglia, neurofibrillary tangles and AGD.DISCUSSION:
We suggest that AGD could explain the atypical course of this dementia considering the fast cognitive decline, the clinical expression and the topography of the lesions.CONCLUSION:
This case illustrates the possible synergistic deleterious effect of this pathology on other causes of dementia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Neurodegenerativas
/
Demência
Tipo de estudo:
Qualitative_research
Limite:
Aged
/
Humans
/
Male
Idioma:
Fr
Ano de publicação:
2010
Tipo de documento:
Article