RECQL5 helicase: connections to DNA recombination and RNA polymerase II transcription.
DNA Repair (Amst)
; 9(3): 345-53, 2010 Mar 02.
Article
em En
| MEDLINE
| ID: mdl-20080450
ABSTRACT
The RecQ family of helicases are traditionally viewed as recombination factors, important for maintaining genome stability. RECQL5 is unique among these proteins in being associated with RNA polymerase II, the enzyme responsible for transcribing all protein-encoding genes in eukaryotes. Here, we describe the possible implications of recent studies and discuss models for RECQL5 function.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recombinação Genética
/
Transcrição Gênica
/
RNA Polimerase II
/
DNA
/
RecQ Helicases
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article