[Safety and immunogenicity of lyophilized live attenuated domestic varicella vaccine].
Zhongguo Yi Miao He Mian Yi
; 15(5): 435-7, 2009 Oct.
Article
em Zh
| MEDLINE
| ID: mdl-20084971
ABSTRACT
OBJECTIVE:
To evaluate the safety and immunogenicity of the lyophilized live attenuated domestic varicella vaccine of Oka strain in Zhejiang province.METHODS:
785 susceptible children aged 1-13 years, who had no history of VZV infection and had not been immunized, were observed. RESULTS The results showed that 2.29% children had adverse reactions after 30 mins of inoculation, 3.69% children had adverse reactions after 4 hours, 3.82% children had adverse reactions after 24 hours, 1.78% children had adverse reactions after 48 hours, 0.25% children had adverse reactions after 72 hours, no adverse reactions were observed after six weeks. There were 3.82% children had fever, The incidence rate of other adverse reactions such as swell and scleroma were low. The vaccine had high sero-converson rate.CONCLUSION:
The results showed that it has good safety and immunogenicity of the live attenuated domestic varicella vaccine.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Varicela
/
Vacina contra Varicela
/
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
Asia
Idioma:
Zh
Ano de publicação:
2009
Tipo de documento:
Article