Evolution of MRSA during hospital transmission and intercontinental spread.
Science
; 327(5964): 469-74, 2010 Jan 22.
Article
em En
| MEDLINE
| ID: mdl-20093474
ABSTRACT
Current methods for differentiating isolates of predominant lineages of pathogenic bacteria often do not provide sufficient resolution to define precise relationships. Here, we describe a high-throughput genomics approach that provides a high-resolution view of the epidemiology and microevolution of a dominant strain of methicillin-resistant Staphylococcus aureus (MRSA). This approach reveals the global geographic structure within the lineage, its intercontinental transmission through four decades, and the potential to trace person-to-person transmission within a hospital environment. The ability to interrogate and resolve bacterial populations is applicable to a range of infectious diseases, as well as microbial ecology.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Estafilocócicas
/
Infecção Hospitalar
/
Genoma Bacteriano
/
Staphylococcus aureus Resistente à Meticilina
Limite:
Humans
País/Região como assunto:
America do norte
/
America do sul
/
Asia
/
Europa
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article