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Successful treatment of life-threatening Candida peritonitis in a child with abdominal non-Hodgkin lymphoma using Efungumab and amphotericin B colloid dispersion.
Krenova, Zdenka; Pavelka, Zdenek; Lokaj, Petr; Skotakova, Jarmila; Kocmanova, Ivana; Teyschl, Otakar; Kren, Leos; Mudry, Peter; Sterba, Jaroslav.
Afiliação
  • Krenova Z; Departments of Pediatric Oncology, University Hospital Brno, Czech Republic. zkrenova@fnbrno.cz
J Pediatr Hematol Oncol ; 32(2): 128-30, 2010 Mar.
Article em En | MEDLINE | ID: mdl-20098335
Invasive fungal infections are serious complications of cancer therapy. We present a case report of a 12-year-old boy diagnosed with abdominal non-Hodgkin lymphoma and fecal and Candida peritonitis during induction chemotherapy. The invasive mycosis was managed using a combined approach of systemic antifungal agents including efungumab and surgical interventions. Efungumab, a recombinant antibody that inhibits extracellular heat shock protein 90, was used in combination with amphotericin B colloid dispersion after the failure of standard approaches.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peritonite / Linfoma não Hodgkin / Candidíase / Anfotericina B / Proteínas de Choque Térmico HSP90 / Neoplasias Abdominais / Anticorpos Monoclonais / Antifúngicos Limite: Child / Humans / Male Idioma: En Ano de publicação: 2010 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peritonite / Linfoma não Hodgkin / Candidíase / Anfotericina B / Proteínas de Choque Térmico HSP90 / Neoplasias Abdominais / Anticorpos Monoclonais / Antifúngicos Limite: Child / Humans / Male Idioma: En Ano de publicação: 2010 Tipo de documento: Article