Bacterial nucleoid-associated proteins, nucleoid structure and gene expression.
Nat Rev Microbiol
; 8(3): 185-95, 2010 Mar.
Article
em En
| MEDLINE
| ID: mdl-20140026
ABSTRACT
Emerging models of the bacterial nucleoid show that nucleoid-associated proteins (NAPs) and transcription contribute in combination to the dynamic nature of nucleoid structure. NAPs and other DNA-binding proteins that display gene-silencing and anti-silencing activities are emerging as key antagonistic regulators of nucleoid structure. Furthermore, it is becoming clear that the boundary between NAPs and conventional transcriptional regulators is quite blurred and that NAPs facilitate the evolution of novel gene regulatory circuits. Here, NAP biology is considered from the standpoints of both gene regulation and nucleoid structure.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bactérias
/
Proteínas de Bactérias
/
Regulação Bacteriana da Expressão Gênica
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article