Antistaphylococcal activities of telavancin tested alone and in combination by time-kill assay.
Antimicrob Agents Chemother
; 54(5): 2201-5, 2010 May.
Article
em En
| MEDLINE
| ID: mdl-20160048
ABSTRACT
Synergy time-kill studies against 40 methicillin-resistant Staphylococcus aureus (MRSA) strains of differing resistance phenotypes were conducted. Subinhibitory concentrations of telavancin were combined with sub-MIC concentrations of other antimicrobial agents that might be used in combination with telavancin to provide Gram-negative coverage. The highest incidence of synergy was found after 24 h with gentamicin (90% of strains), followed by ceftriaxone (88%), rifampin and meropenem (each 65%), cefepime (45%), and ciprofloxacin (38%) for combinations tested at or below the intermediate breakpoint for each agent.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gentamicinas
/
Staphylococcus aureus Resistente à Meticilina
/
Aminoglicosídeos
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Antibacterianos
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article