Infection risk prevention following total knee arthroplasty.
Orthop Traumatol Surg Res
; 96(1): 49-56, 2010 Feb.
Article
em En
| MEDLINE
| ID: mdl-20170857
ABSTRACT
INTRODUCTION:
Implant infection is serious; prevention is mandatory, and requires assessment.The present study assessed the incidence of deep surgical-site infection (SSI) at 1 year following total knee arthroplasty (TKA) and adherence to skin preparation, antibiotic prophylaxis,screening and prevention in case of methicillin-resistant S. aureus (MRSA).HYPOTHESIS:
Adherence to prevention measures reduces infection risk secondary to TKA. MATERIAL ANDMETHODS:
A prospective study of the incidence of SSI following primary TKA was run from December 1st 2005 to December 31st 2006 in a continuous series of 364 operations in 359 patients, excluding cases of septic or aseptic revision. Each implant was followed up for 12 months. Adherence to practice was assessed by independent observers. Antibiotic prophylaxis was assessed; skin preparation was scored (out of 10); MRSA was systematically screened for, and preventive measures were assessed in positive cases. Median follow-up was 12 months.Patients with less than 11 months' FU were contacted by telephone. Median age was 72 years(range, 45-92 years). Eighty-seven percent of patients had ASA scores of 2; 14% were diabetic,and 42% obese. Mean surgery time was 70 min (range, 30-164 min). Among the implants, 81.5% were cemented. Eighty-six percent of operations had NNIS scores of 0. Infection risk linked to theater environment and teams was under control.RESULTS:
Fourteen patients were lost to follow-up and excluded from analysis. The incidence of infection was 1.4% (n = 5/350) (95% CI [0.41-3.22]). Three of the infections were early (-1 month), and two were polymicrobial. Antibiotic prophylaxis was implemented correctly in 99% of cases, with skin preparation scores of 8.75 in 61% of cases and of 10 in 39%. Among the patients, 2.5% were MRSA-positive, none of whom developed infection. Infection prevention measures were applied in only half of the MRSA-positive cases. No MRSA-positive patients developed SSI.DISCUSSION:
SSI incidence in the present series was low, but certainly underestimated. Assessment found good implementation of infection prevention protocols, with SSI occurring randomly with regard to adherence parameters (antibiotic prophylaxis, skin preparation, MRSA status).CONCLUSION:
Our hypothesis could not be confirmed. The study was mandatory for a health-care institution, and indispensable from a legal standpoint. LEVEL OF EVIDENCE Level IV. Prospective prognostic study.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Relacionadas à Prótese
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Artroplastia do Joelho
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Prótese do Joelho
Tipo de estudo:
Etiology_studies
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Guideline
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article