Comparison of colonoscopy and fecal occult blood testing as a first-line screening of colonic lesions in patients with newly diagnosed acromegaly.
J Endocrinol Invest
; 33(8): 530-3, 2010 Sep.
Article
em En
| MEDLINE
| ID: mdl-20186003
ABSTRACT
CONTENT Patients with acromegaly have frequently colonic neoplasms; however, how acromegalic patients should be screened for colonic lesions is still unsettled. AIMS:
To compare fecal occult blood testing (FOBT) and colonoscopy in the screening program of patients with acromegaly.DESIGN:
Colonoscopy and FOBT were performed at the first diagnosis of acromegaly.SETTING:
Tertiary University center. PATIENTS Eighty-five consecutive patients with untreated active acromegaly submitted to colonoscopy and FOBT.RESULTS:
FOBT, which was positive in 16 (18.8%) out of 85 patients, identified 2 patients with colonic adenocarcinoma and 2 with adenoma; the remaining 12 patients had no detectable colonic lesions. Colonoscopy revealed colonic lesions in 29 patients 3 (3.5%) cancers, 11 (12.9%) adenomas, and 15 (17.6%) hyperplastic polyps. The remaining 56 acromegalic patients had no detectable lesions. A patient with cancer and 9 patients with adenoma were missed if screened only by FOBT.CONCLUSIONS:
Colonoscopy is superior to FOBT in detecting colonic lesions at the first diagnosis of acromegaly.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acromegalia
/
Pólipos do Colo
/
Colonoscopia
/
Neoplasias do Colo
/
Sangue Oculto
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article