The first complete papillomavirus genome characterized from a marsupial host: a novel isolate from Bettongia penicillata.
J Virol
; 84(10): 5448-53, 2010 May.
Article
em En
| MEDLINE
| ID: mdl-20200246
ABSTRACT
The first fully sequenced papillomavirus (PV) of marsupials, tentatively named Bettongia penicillata papillomavirus type 1 (BpPV1), was detected in papillomas from a woylie (Bettongia penicillata ogilbyi). The circular, double-stranded DNA genome contains 7,737 bp and encodes 7 open reading frames (ORFs), E6, E7, E1, E2, E4, L2, and L1, in typical PV conformation. BpPV1 is a close-to-root PV with L1 and L2 ORFs most similar to European hedgehog PV and bandicoot papillomatosis carcinomatosis virus types 1 and 2 (BPCV1 and -2). It appears that the BPCVs arose by recombination between an ancient PV and an ancient polyomavirus more than 10 million years ago.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Papiloma
/
Infecções Tumorais por Vírus
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DNA Viral
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Genoma Viral
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Polyomavirus
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Infecções por Polyomavirus
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Potoroidae
Limite:
Animals
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article