DNA-functionalized solid state nanopore for biosensing.
Nanotechnology
; 21(14): 145102, 2010 Apr 09.
Article
em En
| MEDLINE
| ID: mdl-20220223
ABSTRACT
The possible use of nanopores for single DNA molecules biosensing has been demonstrated, but much remains to do in order to develop advanced engineered devices with enhanced stability, and controlled geometry and surface properties. Here we present morphological and electrical characterization of solid state silicon nitride nanopores fabricated by focused ion beam direct milling and chemically functionalized by probe oligonucleotides, with the final aim of developing a versatile tool for biosensing and gene expression profiling.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Técnicas Biossensoriais
/
Nanoestruturas
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article