Transition-metal-free electrophilic amination between aryl Grignard reagents and N-chloroamines.
Org Lett
; 12(7): 1516-9, 2010 Apr 02.
Article
em En
| MEDLINE
| ID: mdl-20222741
ABSTRACT
In the presence of N,N,N',N'-tetramethylethylenediamine (TMEDA) as an additive, easily prepared and handled N-chloroamines react with aryl Grignard reagents to give a variety of arylamines in good to excellent yields. Functional groups such as ester and nitrile are compatible under the reaction conditions.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
/
Cloraminas
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article