Myxofibrosarcoma of the orbit: a clinicopathologic case report.

ABSTRACT

A 27-year-old woman developed a rapidly progressive left orbital tumor that extended in the cranial fossa. MRI revealed a heterogenous enhancing lesion confined to the left frontal bone and superior orbit. An incisional biopsy was performed, and histopathologic examination of the specimen showed findings diagnostic of a high-grade myxofibrosarcoma. Complete excision with postoperative adjuvant radiation therapy and chemotherapy was performed, and the patient had no evidence of tumor recurrence within 6 months' follow-up. Myxofibrosarcoma is a fibroblast-derived soft tissue neoplasm with up to a 60% local recurrence rate, and metastasis may be associated with intermediate to high-grade tumors.