Local intra-arterial administration of urokinase in the treatment of a feline distal aortic thromboembolism.
J Vet Med Sci
; 72(9): 1209-11, 2010 Sep.
Article
em En
| MEDLINE
| ID: mdl-20379085
ABSTRACT
A 5-year old neutered male cat was admitted to our hospital in the early morning with sudden onset of bilateral hindlimbs paralysis. Conservative anticoagulant therapy using heparin, warfarin, and dipyridamole, and thrombolytic therapy with urokinase administered by intravenous infusion were started. However, no improvement was noted even after 2 days of treatment, and the cat was started on local intra-arterial administration of urokinase via a catheter on disease day 3. Successful thrombolysis could be accomplished by this approach, and the motor function of both hindlimbs recovered on disease day 5. The cat could be discharged on disease day 9. Complications such as hemorrhage and hyperkalemia were not observed during the thrombolytic therapy. These results suggest that local intra-arterial administration of urokinase may be an effective approach for the treatment of FATE.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tromboembolia
/
Ativador de Plasminogênio Tipo Uroquinase
/
Doenças do Gato
Limite:
Animals
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article