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[Surgical management of bilateral Wilms' tumor: our experience with 18 cases]. / Manejo quirúrgico del tumor de Wilms bilateral: nuestra experiencia con 18 casos.
Fernández-Pineda, I; Cabello Laureano, R; Fernández-Hurtado, M A; Granero Cendón, R; Tuduri Limousín, I; Morcillo Azcárate, J; Aspiazu Salinas, D; García Vallés, C; De Agustín Asensio, J C.
Afiliação
  • Fernández-Pineda I; Servicio de Cirugía Pediátrica, Hospital Infantil Universitario Virgen del Rocío, Sevilla.
Cir Pediatr ; 22(4): 186-8, 2009 Oct.
Article em Es | MEDLINE | ID: mdl-20405651
ABSTRACT

AIM:

To show our experience in the surgical management of bilateral Wilms' tumor.

METHODS:

We have reviewed the medical records of 18 patients diagnosed of bilateral Wilms' tumor between 1971 and 2007, evaluating age, sex, clinical situation, imaging studies, histology, treatment, complications and follow-up.

RESULTS:

65% of patients with synchronous Wilms' tumor was stage I-II, 30% stage III and 5% stage IV. 100% of patients with metachronous Wilms' tumor was stage I-II. All the tumors had favourable histology. Surgical complications were 4 bowel pseudobstructions, 2 ureteropielic fistulae and 1 urinary cyst. 15 patients are alive (83%) with a mean follow-up of 12 years. 3 of these patients had a renal trasplant with a good evolution. One patient died of a progressive renal failure and two patients died of the evolution of the oncological disease.

CONCLUSIONS:

Preoperative chemotherapy allows a conservative surgical resection with a high overall survival (80-90%). Individualized surgical treatment offers a conservative surgical resection with a lower incidence of long-term renal failure.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tumor de Wilms / Neoplasias Renais / Neoplasias Primárias Múltiplas Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: Es Ano de publicação: 2009 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tumor de Wilms / Neoplasias Renais / Neoplasias Primárias Múltiplas Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: Es Ano de publicação: 2009 Tipo de documento: Article