Synthesis and antimicrobial activities of two novel amino sugars derived from chloraloses.
Carbohydr Res
; 345(11): 1617-21, 2010 Jul 19.
Article
em En
| MEDLINE
| ID: mdl-20488435
ABSTRACT
The synthesis of 5-amino-5-deoxy-1,2-O-(S)-trichloroethylidene-beta-L-arabinofuranose and 6-amino-6-deoxy-1,2-O-(S)-trichloroethylidene-alpha-D-glucofuranose is described by a simple three- or four-step route. Antibacterial potency of the new compounds was determined using an inhibition zone diameter test. The results show that these compounds have a broad-spectrum activity against Gram-positive, Gram-negative bacteria and Candida albicans.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cloralose
/
Amino Açúcares
/
Anti-Infecciosos
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article