[Investigation of biotechnological strains of microorganisms for their hygienic standardization].

ABSTRACT

By analyzing the findings and databases on the hygienic standardization of industrial microorganisms, the authors have improved a research program for industrial strains on substantiating their safe exposure levels in workplace and ambient airs. A shortened program is proposed to investigate gram-positive bacteria and nocardioformic actinomycetes (Lactobacillus, Micrococcus, Propionibacterim, Brevibacterim, Rhodococcus), which have no negative effect. It is necessary to study gram-negative bacteria and micromycetes (Pseudomonas, Alcaligenes, Acinetobacter, Arthrobacter, Aspergillus, Penicillum, Candida), which have pronounced immunotropic and dysbiotic properties by the full program, by including the evaluation of all observed negative effects. On the basis of this group, the priority microorganisms that confer a real danger to workers' health in developing allergic diseases have been listed.