A parallel algorithm to compute chemical organizations in biological networks.
Bioinformatics
; 26(14): 1788-9, 2010 Jul 15.
Article
em En
| MEDLINE
| ID: mdl-20501552
ABSTRACT
SUMMARY:
Analysing genome-scale in silico models with stoichiometry-based methods is computationally demanding. The current algorithms to compute chemical organizations in chemical reaction networks are limited to small-scale networks, prohibiting a thorough analysis of large models. Here, we introduce a parallelized version of the constructive algorithm to determine chemical organizations. The algorithm is implemented in the Standard C programming language and parallelized using the message passing interface (MPI) protocol. The resulting code can be executed on computer clusters making use of an arbitrary number of processors. The algorithm is parallelized in an embarrassing parallel manner, providing good scalability.AVAILABILITY:
An implementation of the algorithm including source code can be obtained from http//www.minet.uni-jena.de/csb/prj/ot/tools
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Algoritmos
/
Modelos Biológicos
/
Modelos Químicos
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article