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A new approach for PEGylation of dendrimers.
Khambete, Hemant; Gautam, Surya P; Karthikeyan, C; Ramteke, Suman; Hari Narayana Moorthy, N S; Trivedi, Piyush.
Afiliação
  • Khambete H; School of Pharmaceutical Sciences, Rajiv Gandhi Technical University, Airport Bypass Road, Gandhi Nagar, Bhopal (MP) 462 036, India.
Bioorg Med Chem Lett ; 20(14): 4279-81, 2010 Jul 15.
Article em En | MEDLINE | ID: mdl-20558063
Dendrimers have emerged as one of the most interesting themes for researchers as a result of unique functional architecture and macromolecular characteristics. The reported methods of PEGylation are very time consuming and required multisteps for synthesis. In present work we have synthesized PEGylated polyamidoamine (PAMAM) dendrimers using epichlorohydrin as a linker. The PEGylated dendrimers were evaluated for color reaction UV, IR and NMR studies and compared with standard data.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Dendrímeros Idioma: En Ano de publicação: 2010 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Dendrímeros Idioma: En Ano de publicação: 2010 Tipo de documento: Article