[An analysis of the characteristics and etiology of hand, foot and mouth disease in a Guangzhou sentinel hospital from May to December, 2008].
Nan Fang Yi Ke Da Xue Xue Bao
; 30(6): 1333-5, 2010 Jun.
Article
em Zh
| MEDLINE
| ID: mdl-20584671
ABSTRACT
OBJECTIVE:
To analyze the characteristics and etiology of hand, foot and mouth disease (HFMD) in a sentinel hospital of Guangzhou.METHODS:
The epidemiological data and clinical specimens were collected from May to December, 2008 for virological investigations (viral isolation, RT-PCR and molecular identification) and phylogenetic analysis.RESULTS:
A total of 309 clinical cases were reported, and the incidence was the highest in 2-4-year-old children, among whom only 15 developed complications, with human enterovirus 71 (HEV71) as the main pathogen (64.7%). Phylogenetic analysis indicated that ten Guangzhou EV71 isolates belonged to Cluster C4a.CONCLUSION:
HFMD is an important infectious disease in children resulting from infections by HEV71 as the main pathogen in 2008, and the Guangzhou C4a strains co-evolved with the isolates from other provinces in China and the neighboring countries.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Enterovirus Humano A
/
Doença de Mão, Pé e Boca
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
Zh
Ano de publicação:
2010
Tipo de documento:
Article