Cytogenetic analysis of experimental interspecies goat-sheep chimera.
J Hered
; 82(3): 244-5, 1991.
Article
em En
| MEDLINE
| ID: mdl-2061596
ABSTRACT
Chromosomal analysis was carried out on blood lymphocytes, skin fibroblasts, and germinal cells of an interspecies goat-sheep chimera. This chimera was produced by aggregation of blastomeres of goat and sheep embryos. A cell chimerism 54,XX/60,XY was found in blood lymphocytes and skin fibroblasts. At birth the percentage of lymphocytes with karyotype 54,XX (sheep) amounted to 80% and with karyotype 60,XY (goat) to 20%. With age the percentage of lymphocytes with chromosome complement 54,XX increased, so that at 18 months it was 94% sheep and 6% goat. At the same age, in skin fibroblasts the percentage of cells with goat karyotype reached 25%. Analysis of germinal cells showed in spermatogonia the presence of only karyotype 60,XY and in primary spermatocytes of 29 autosomal bivalents and the sex bivalent XY.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cabras
/
Ovinos
/
Quimera
Limite:
Animals
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article