One-pot multicomponent synthesis and anti-microbial evaluation of 2'-(indol-3-yl)-2-oxospiro(indoline-3,4'-pyran) derivatives.

Nandakumar, A; Thirumurugan, Prakasam; Perumal, Paramasivan T; Vembu, P; Ponnuswamy, M N; Ramesh, P

Nandakumar, A; Thirumurugan, Prakasam; Perumal, Paramasivan T; Vembu, P; Ponnuswamy, M N; Ramesh, P.

Afiliação

Nandakumar A; Organic Chemistry Division, Central Leather Research Institute, Adyar, Chennai 600 020, Tamil Nadu, India.

Bioorg Med Chem Lett ; 20(14): 4252-8, 2010 Jul 15.

Article em En | MEDLINE | ID: mdl-20621732

ABSTRACT

ABSTRACT

A simple and efficient method for the one-pot three-component synthesis of new spirooxindoles in room temperature is described. The newly synthesized spirooxindoles were screened for anti-microbial activity and the results are good on comparison with of standard antibacterial compounds.

Assuntos

Anti-Infecciosos/química; Anti-Infecciosos/farmacologia; Indóis/química; Indóis/farmacologia; Testes de Sensibilidade Microbiana; Modelos Moleculares

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indóis / Anti-Infecciosos Idioma: En Ano de publicação: 2010 Tipo de documento: Article

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