Antibacterial activity of flavonoids from the stem bark of Erythrina caffra thunb.
Phytother Res
; 25(1): 46-8, 2011 Jan.
Article
em En
| MEDLINE
| ID: mdl-20623615
ABSTRACT
The antibacterial activity of the stem bark of Erythrina caffra Thunb. was investigated against different bacterial strains. The antibacterial activity was determined by a micro broth dilution assay. Antibacterial compounds were isolated and identified using a Bruker Avance III LPO NMR spectrometer. Four known flavonoids, abyssione-V 4'-O-methyl ether, 6,8-diprenylgenistein, alpinumisoflavone and burttinone, were isolated. All the compounds were active against both Gram-negative and Gram-positive bacteria. The minimum inhibitory concentration values obtained (MIC) ranged from 3.9 µg/mL to 125 µg/mL. This is the first report of antibacterial activity of burttinone and the isolation of these compounds from E. caffra.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Flavonoides
/
Erythrina
/
Antibacterianos
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article