Your browser doesn't support javascript.
loading
Analgesic activity of Heliopsis longipes and its effect on the nervous system.
Cilia-López, V G; Juárez-Flores, B I; Aguirre-Rivera, J R; Reyes-Agüero, J A.
Afiliação
  • Cilia-López VG; Programa Multidisciplinario de Posgrado en Ciencias Ambientales, UASLP San Luis Potosí, México.
Pharm Biol ; 48(2): 195-200, 2010 Feb.
Article em En | MEDLINE | ID: mdl-20645840
Heliopsis longipes S.F. Blake (Asteraceae: Heliantheae) (chilcuague) is used in Mexican traditional medicine against parasites and to alleviate tooth and muscle pains. Its biocide effect has already been experimentally demonstrated; however, its analgesic action and its action on the nervous system (NS) have not been investigated yet. The objectives of this study were to evaluate the analgesic action of affinin and the H. longipes root ethanol extract, as well as their effects on the NS using an animal model. The ethanol extract was obtained by maceration, and affinin was purified from it through chromatographic techniques. Chemical and thermal analgesia were used to assess their analgesic proprieties. Irwin's test was used to evaluate their stimulating or depressing effects. The ethanol extract and affinin displayed analgesic action similar to ketorolac and stimulating effect comparable to caffeine on the nervous system of adult mice.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Extratos Vegetais / Analgésicos não Narcóticos / Asteraceae / Fitoterapia / Sistema Nervoso Tipo de estudo: Prognostic_studies Limite: Animals País/Região como assunto: Mexico Idioma: En Ano de publicação: 2010 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Extratos Vegetais / Analgésicos não Narcóticos / Asteraceae / Fitoterapia / Sistema Nervoso Tipo de estudo: Prognostic_studies Limite: Animals País/Região como assunto: Mexico Idioma: En Ano de publicação: 2010 Tipo de documento: Article