Metal-free regioselective oxidative biaryl coupling leading to head-to-tail bithiophenes: reactivity switching, a concept based on the iodonium(III) intermediate.
Org Lett
; 12(17): 3804-7, 2010 Sep 03.
Article
em En
| MEDLINE
| ID: mdl-20690618
ABSTRACT
A new synthetic concept for obtaining unsymmetrical biaryl coupling products by an oxidative method is reported. Our synthetic strategy casts light on the reaction intermediate for switching the reactivity of 3-substituted thiophenes. On the basis of this strategy, a novel direct method for the synthesis of head-to-tail bithiophenes using hypervalent iodine(III) reagents has been developed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tiofenos
/
Iodo
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article