[Clinical and ultrastructural studies on 8 cases of methamidophos toxicologic myopathy].
Zhonghua Bing Li Xue Za Zhi
; 19(4): 303-5, 1990 Dec.
Article
em Zh
| MEDLINE
| ID: mdl-2081358
ABSTRACT
Clinically, there was pain or numbness in the lower limbs at first; then followed by muscular weakness and symmetrical wasting of the small muscles of the hands and lower limbs. Electromyography showed myogenic changes in all the 8 cases and biopsies indicated atrophy of muscle fibers. The most prominent ultrastructural change was presence of abnormal accumulation of myofibers with regeneration and necrosis. There was decrease of mitochondria and glycogen even disappearance of M--line or Z--line. The pathogenesis is considered due to cell--mediated--immunity and direct toxic effect.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Organotiofosforados
/
Inseticidas
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Músculos
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Doenças Musculares
Limite:
Adult
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Female
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Humans
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Male
Idioma:
Zh
Ano de publicação:
1990
Tipo de documento:
Article