Metastatic squamous cell carcinoma of the oropharynx in a child with a mutation in the Connexin 26 gene.
J Pediatr Hematol Oncol
; 33(5): 387-9, 2011 Jul.
Article
em En
| MEDLINE
| ID: mdl-20829717
Pediatric oral squamous cell carcinoma is an extremely rare occurence. In our report, we describe a 6-year-old White female with sensorineural hearing loss found to have a Connexin 26 gene mutation who developed a well-differentiated squamous cell carcinoma of the hard palate with metastatic disease to submandibular lymph nodes and the lungs. This association emphasizes the need to consider Connexin 26 gene mutations in children who develop oral squamous cell carcinoma and to monitor for oral squamous cell carcinoma in children with Connexin 26 gene mutations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma de Células Escamosas
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Neoplasias Palatinas
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Neoplasias Orofaríngeas
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Conexinas
Limite:
Child
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Female
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Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article