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Evaluation of the Ves-Matic Cube 200 erythrocyte sedimentation method: comparison with Westergren-based methods.
Curvers, Joyce; Kooren, Jurgen; Laan, Maartje; van Lierop, Edwin; van de Kerkhof, Daan; Scharnhorst, Volkher; Herruer, Martien.
Afiliação
  • Curvers J; Clinical Laboratory, Catharina Hospital Eindhoven, PO Box 1350, 5602 ZA Eindhoven, the Netherlands.
Am J Clin Pathol ; 134(4): 653-60, 2010 Oct.
Article em En | MEDLINE | ID: mdl-20855647
The erythrocyte sedimentation rate (ESR) is still a widely used parameter for acute phase inflammation. Recently, new methods based on direct undiluted measurement of ESR in a standard EDTA tube have been developed. We evaluated the analytic performance of one of these new methods, the Ves-Matic Cube 200 (Diesse Diagnostica Senese, Siena, Italy), and compared it with several established Westergren-based diluted methods. The Ves-Matic Cube 200 showed a poor correlation (r = 0.83) with the International Council for Standardization in Haematology Westergren reference method, mainly caused by a considerable negative bias at low ESR levels. Moreover, a random bias was found at higher ESR levels that correlated with hematocrit levels, suggesting a differential influence of packed cell volume on the Ves-Matic Cube 200 results compared with Westergren results. We conclude that the Ves-Matic Cube 200 method is not interchangeable with Westergren-based diluted methods and generates ESR results that are too deviant to be clinically acceptable.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sedimentação Sanguínea / Inflamação Tipo de estudo: Clinical_trials / Diagnostic_studies / Evaluation_studies Idioma: En Ano de publicação: 2010 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sedimentação Sanguínea / Inflamação Tipo de estudo: Clinical_trials / Diagnostic_studies / Evaluation_studies Idioma: En Ano de publicação: 2010 Tipo de documento: Article