A novel method for the genome-wide high resolution analysis of DNA damage.
Nucleic Acids Res
; 39(2): e10, 2011 Jan.
Article
em En
| MEDLINE
| ID: mdl-21062813
ABSTRACT
DNA damage occurs via endogenous and exogenous genotoxic agents and compromises a genome's integrity. Knowing where damage occurs within a genome is crucial to understanding the repair mechanisms which protect this integrity. This paper describes a new development based on microarray technology which uses ultraviolet light induced DNA damage as a paradigm to determine the position and frequency of DNA damage and its subsequent repair throughout the entire yeast genome.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dano ao DNA
/
Análise de Sequência com Séries de Oligonucleotídeos
/
Reparo do DNA
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article