Whole-brain perfusion measurement using 320-detector row computed tomography in patients with cerebrovascular steno-occlusive disease: comparison with 15O-positron emission tomography.
J Comput Assist Tomogr
; 34(6): 830-5, 2010.
Article
em En
| MEDLINE
| ID: mdl-21084896
ABSTRACT
OBJECTIVE:
The 320-detector row computed tomography (CT) can provide whole-brain CT perfusion (CTP) maps with continuous angiographic images by performing a single dynamic scan. We investigated the reliability of CTP cerebral blood flow (CTP-CBF) with 320-detector row CT by comparing findings with O-positron emission tomography (PET-CBF).METHODS:
Whole-brain CTP and PET were performed in 10 patients with chronic unilateral steno-occlusive disease. We compared absolute and relative CBF values of bilateral middle cerebral artery territories between CTP and PET.RESULTS:
Although mean CTP-CBF values were approximately 30% lower than mean PET-CBF values, the mean ischemic-to-nonischemic CBF ratios of CTP and PET were almost identical (P = 0.804). Regression analysis showed a significant correlation between CTP-CBF and PET-CBF values for each patient (r = 0.52-0.85, P < 0.001).CONCLUSIONS:
Whole-brain CTP using 320-detector row CT is useful for evaluating the degree of ischemia for the entire brain with chronic cerebrovascular disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arteriopatias Oclusivas
/
Tomografia Computadorizada por Raios X
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Circulação Cerebrovascular
/
Transtornos Cerebrovasculares
Limite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article