[Sarcoidosis: changing insights in therapy]. / Sarcoïdose: verandering in therapeutische inzichten.
Ned Tijdschr Geneeskd
; 154(47): A1685, 2010.
Article
em Nl
| MEDLINE
| ID: mdl-21118599
ABSTRACT
Sarcoidosis is a granulomatous disease of unknown etiology. Standard treatment with immune suppressants such as glucocorticoids is started when vital organ function is threatened. Biotechnology has resulted in new treatments ('biologicals'), in particular monoclonal antibodies, that may be effective in the treatment of sarcoidosis. In patients with sarcoidosis, only the use of monoclonal antibodies that block tumour necrosis factor (TNF) has been studied scientifically, other biologicals hardly at all. TNF-blockers are used at present in patients with therapy refractory sarcoidosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sarcoidose
/
Resistência a Medicamentos
/
Fator de Necrose Tumoral alfa
/
Quimioterapia Combinada
/
Anticorpos Monoclonais
Limite:
Humans
Idioma:
Nl
Ano de publicação:
2010
Tipo de documento:
Article