Analgesic use during pregnancy and risk of infant leukaemia: a Children's Oncology Group study.
Br J Cancer
; 104(3): 532-6, 2011 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-21157452
ABSTRACT
BACKGROUND:
Infant leukaemia is likely initiated in utero.METHODS:
We examined whether analgesic use during pregnancy was associated with risk by completing telephone interviews of the mothers of 441 infant leukaemia cases and 323 frequency-matched controls, using unconditional logistic regression.RESULTS:
With the exception of a reduced risk for infant acute myeloid leukaemias with non-aspirin non-steroidal anti-inflammatory drugs (NSAID) use early in pregnancy (odds ratios=0.60; confidence intervals 0.37-0.97), no statistically significant associations were observed for aspirin, non-aspirin NSAIDs, or acetaminophen use in early pregnancy or after knowledge of pregnancy.CONCLUSION:
Overall, analgesic use during pregnancy was not significantly associated with the risk of infant leukaemia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Efeitos Tardios da Exposição Pré-Natal
/
Leucemia
/
Analgésicos
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Infant
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Middle aged
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Newborn
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Pregnancy
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article