[Cardiovascular manifestations in Chinese patients with hypereosinophilic syndrome].
Zhonghua Xin Xue Guan Bing Za Zhi
; 38(10): 905-8, 2010 Oct.
Article
em Zh
| MEDLINE
| ID: mdl-21176634
ABSTRACT
OBJECTIVE:
To evaluate the cardiovascular involvements in Chinese patients with hypereosinophilic syndrome.METHOD:
We respectively reviewed 149 inpatients with hypereosinophilic syndrome admitted to Peking Union Medical College Hospital and analyzed the cardiovascular involvements in these patients.RESULTS:
Cardiac abnormalities was evidenced in 32.9% patients (49/149). The ratio of male vs female was 3415. The average age of the patients was (41.3 ± 16.9) years and course of disease was (26.4 ± 72.3) months. Cardiovascular involvements included ST segment and/or T wave (ST-T) ischemic changes, arrhythmia, myocardial injury, cardiac thrombosis, pericardial effusion, pulmonary hypertension, valve disorder, vein or artery thrombosis. After glucocorticoid and/or chemotherapeutic agents and treatment for symptoms, 11 (22.4%) patients achieved remission but have recurrent attacks and 3 (6.1%) patients died from failure in treatment. The prognosis in patients with echocardiogram abnormalities were poorer than those only with electrocardiogram abnormalities (P < 0.05).CONCLUSIONS:
Cardiovascular involvements are common in patients with hypereosinophilic syndrome and the manifestation of these involvement is various. Cardiovascular complications of HES are a major source of morbidity and mortality in these disorders.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome Hipereosinofílica
/
Cardiopatias
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Middle aged
Idioma:
Zh
Ano de publicação:
2010
Tipo de documento:
Article