Current progress in pharmacogenetics.
Br J Clin Pharmacol
; 71(6): 824-31, 2011 Jun.
Article
em En
| MEDLINE
| ID: mdl-21235621
ABSTRACT
The study of genetic variation has the potential to aid understanding of the mechanisms underlying the observed inter-individual variation in drug response and by which idiosyncratic adverse effects occur. In this review, we outline current progress in pharmacogenetics using examples to highlight both mechanisms of influence of polymorphisms and research strategies for their detection. In the final sections we discuss contemporary challenges for both researchers and clinicians.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Farmacogenética
/
Polimorfismo Genético
/
Variação Genética
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Regulação da Expressão Gênica
/
Genoma
Limite:
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article