Functionalisation of aldehydes via aerobic hydroacylation of azodicarboxylates 'on' water.
Chem Commun (Camb)
; 47(11): 3269-71, 2011 Mar 21.
Article
em En
| MEDLINE
| ID: mdl-21286608
ABSTRACT
Herein we report the functionalisation of aldehydes via hydroacylation of azodicarboxylates. A range of functionalised aldehydes are employed as the limiting reagent including chiral non-racemic aldehydes bearing α-stereocentres which are functionalised giving access to enantiomerically pure products. The resultant hydrazides can be employed as acyl donors in the synthesis of amides.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácidos Carboxílicos
/
Aldeídos
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article