[Hormonal treatment effectivity in hyperandrogenic syndrome]. / Efekt hormonálnej liecby hyperandrogénneho syndrómu.
Ceska Gynekol
; 75(5): 481-5, 2010 Oct.
Article
em Sk
| MEDLINE
| ID: mdl-21374929
ABSTRACT
OBJECTIVE:
To evaluate effectiveness of hormonal treatment of hyperandrogenic syndrome (HAS).DESIGN:
Prospective randomized study.SETTING:
Department of Gynecology and Obstetrics, Jessenius Faculty of Medicine, Comenius University, Martin, Slovak Republic.METHODS:
We assessed effect of one-year-long hormonal treatment on menstrual cycles (MC), clinical signs of HAS, and ultrasound finding (USG) in 90 patients with HAS. Patients were divided into three groups with 30 females A--35 microg ethinylestradiol (EE) with 2.0 mg cyproterone acetate/day; B--30 microg EE with 2.0 mg dienogest/day; C--30 microg EE with 3.0 mg drospirenone/day.RESULTS:
It was achieved a positive effect on MC regularity in every group during the first six months of treatment (p < 0.001). Signs of hirsutism, virilization, and USG finding were significantly better in group A.CONCLUSION:
The most effective hormonal treatment in our study was the combination of 35 microg EE with 2.0 mg cyproterone acetate/day.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Ovário Policístico
/
Acetato de Ciproterona
/
Hiperandrogenismo
/
Estrogênios
/
Etinilestradiol
/
Antagonistas de Androgênios
/
Androstenos
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
Idioma:
Sk
Ano de publicação:
2010
Tipo de documento:
Article