Immunocytochemical localization of claudin-1 in the maturation ameloblasts of rat incisors.
Front Physiol
; 1: 150, 2010.
Article
em En
| MEDLINE
| ID: mdl-21423390
ABSTRACT
Claudin-1 is a tight junction transmembrane protein. Its localization in the maturation ameloblasts of rat incisors was examined by immunofluorescence microscopy. Distal junction area of ruffle-ended ameloblasts (RA) and the Golgi apparatus of a sub-population of smooth-ended ameloblasts (SA) and RAs stained positive with anti-claudin-1 antibodies. Since it has been shown that ameloblasts repeatedly alternate between an SA and an RA morphology during enamel maturation, the presence of claudin-1 in the Golgi cisterns may indicate the presence of tight junction precursors before transportation to the junctional area.
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Coleções:
01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article