A comparison of recombinant receptor-reporter gene bioassays and a total estrogen enzyme linked immunosorbent assay for the rapid screening of estrogenic activity in natural and waste waters.
Bull Environ Contam Toxicol
; 86(5): 461-4, 2011 May.
Article
em En
| MEDLINE
| ID: mdl-21442212
ABSTRACT
In this study, we compared the performance as screening tools of two yeast-based recombinant receptor-reporter gene bioassays with a commercial ELISA kit for measurement of total estrogens. For WWTP effluents there was a very good correlation between the measured total estrogen concentrations (ELISA) and estrogenic activity by the hERα bioassay (r(2)=0.93), but not for the medERα bioassay (r(2)=0.50). For freshwater samples, the correlations between bioassay response and ELISA ES measurements were very good (r(2)>0.95). There was no correlation between bioassay response and ELISA ES measurements for estuarine samples.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poluentes Químicos da Água
/
Monitoramento Ambiental
/
Estrogênios
/
Disruptores Endócrinos
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article